Procalcitonin

Procalcitonin: seeking a niche

For over a decade there has been intense interest given to the role of procalcitonin in the diagnosis and management of sepsis in critically ill patients. Early opinions strongly supported the diagnostic role but data accumulating from numerous subsequent studies are less supportive, even when used in very selective settings. Although there remains sufficient reason to support the use of procal...

Analyzed for Procalcitonin (liaison

Brahms PCT), yielding a result of 0.88 g/L, slightly higher than the cutoff value (0.58 g/L). The crossreactivity with procalcitonin might be more likely in our sample measured with a polyclonal assay. Other interferences cannot be excluded. The 2 CT assays give markedly different results. The introduction of an internationally agreed upon standard would contribute to optimizing the CT assay, t...

Procalcitonin in takayasu arteritis.

Update on Procalcitonin Measurements

Procalcitonin (PCT) is used as a biomarker for the diagnosis of sepsis, severe sepsis and septic shock. At the same time, PCT has also been used to guide antibiotic therapy. This review outlines the main indications for PCT measurement and points out possible pitfalls. The classic indications for PCT measurement are: (i) confirmation or exclusion of diagnosis of sepsis, severe sepsis, or septic...

Serum procalcitonin level: clinical significance.

Procalcitonin, a propeptide of calcitonin, is an important host response biomarker indicative of infection. In particular, it aids in assessing the severity of infection and its prognosis [2, 3]. Using this severity marker to differentiate two infectious diseases seems unjustified. Both the diseases can have varying degrees of severity and may also be confounded by factors such as immunocomprom...